diff --git a/Mage.Sets/src/mage/cards/a/AnyaMercilessAngel.java b/Mage.Sets/src/mage/cards/a/AnyaMercilessAngel.java
index b1bdf5f02fe..c845d99371f 100644
--- a/Mage.Sets/src/mage/cards/a/AnyaMercilessAngel.java
+++ b/Mage.Sets/src/mage/cards/a/AnyaMercilessAngel.java
@@ -76,7 +76,9 @@ enum AnyaMercilessAngelDynamicValue implements DynamicValue {
         int startingLifeTotal = game.getStartingLife();
         for (UUID opponentId : game.getOpponents(controller.getId())) {
             Player opponent = game.getPlayer(opponentId);
-            if (opponent != null && opponent.getLife() < startingLifeTotal / 2) {
+            if (opponent != null 
+                    && opponent.isInGame()
+                    && opponent.getLife() < startingLifeTotal / 2) {
                 opponentCount++;
             }
         }
diff --git a/Mage.Sets/src/mage/cards/v/ViridianBetrayers.java b/Mage.Sets/src/mage/cards/v/ViridianBetrayers.java
index 4ce8889986c..0e448b1ddce 100644
--- a/Mage.Sets/src/mage/cards/v/ViridianBetrayers.java
+++ b/Mage.Sets/src/mage/cards/v/ViridianBetrayers.java
@@ -1,4 +1,3 @@
-
 package mage.cards.v;
 
 import java.util.Set;
@@ -60,7 +59,9 @@ enum PoisonedCondition implements Condition {
         Set<UUID> opponents = game.getOpponents(source.getControllerId());
         for (UUID opponentUuid : opponents) {
             Player opponent = game.getPlayer(opponentUuid);
-            if (opponent != null && opponent.getCounters().getCount(CounterType.POISON) > 0) {
+            if (opponent != null
+                    && opponent.isInGame()
+                    && opponent.getCounters().getCount(CounterType.POISON) > 0) {
                 return true;
             }
         }
diff --git a/Mage/src/main/java/mage/abilities/condition/common/XorLessLifeCondition.java b/Mage/src/main/java/mage/abilities/condition/common/XorLessLifeCondition.java
index 2a0837cf6f9..3e177e0818b 100644
--- a/Mage/src/main/java/mage/abilities/condition/common/XorLessLifeCondition.java
+++ b/Mage/src/main/java/mage/abilities/condition/common/XorLessLifeCondition.java
@@ -28,11 +28,17 @@ public class XorLessLifeCondition implements Condition {
     @Override
     public boolean apply(Game game, Ability source) {
         boolean conditionApplies = false;
+        
+        /*
+        104.5. If a player loses the game, that player leaves the game.
+        Once a player leaves the game, their life check is no longer valid.  IE Anya, Merciless Angel
+        */
 
         switch ( this.type ) {
             case AN_OPPONENT:
                 for ( UUID opponentUUID : game.getOpponents(source.getControllerId()) ) {
-                    conditionApplies |= game.getPlayer(opponentUUID).getLife() <= amount;
+                    conditionApplies |= game.getPlayer(opponentUUID).isInGame() 
+                            && game.getPlayer(opponentUUID).getLife() <= amount;
                 }
                 break;
             case CONTROLLER:
@@ -46,7 +52,8 @@ public class XorLessLifeCondition implements Condition {
                 PlayerList playerList = game.getState().getPlayersInRange(source.getControllerId(), game);
                 for ( UUID pid : playerList ) {
                     Player p = game.getPlayer(pid);
-                    if (p != null) {
+                    if (p != null
+                            && p.isInGame()) {
                         if (maxLife < p.getLife()) {
                             maxLife = p.getLife();
                         }